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Computational biology

Decode Life: AI & Computational Biology

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Regression and classification

A regression output is numerical, such as biomarker concentration; a classifier estimates a class or class probability.

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A regression output is numerical, such as biomarker concentration; a classifier estimates a class or class probability. Choose a baseline before a complex model and inspect whether the target is measured reliably. Features available only after diagnosis cannot support a model meant for prediagnosis screening. State the intended use before deciding which model to fit.

Worked example

A prediagnosis screen cannot use a biopsy result obtained after diagnosis. Compare a simple biomarker threshold with a model using only measurements available at screening time.