Research topic
Glial-like tumors with diverse molecular entities and context-dependent neural signaling.
Independent educational guide. Not affiliated with or endorsed by the universities, professors or laboratories described here. This collection reflects the material currently mapped on Socratic Learn.
Research at the intersection of neurodevelopment, glioma biology, neural activity, tumor microenvironment signaling, cancer neuroscience, and mechanism-guided therapies.
9 lessons · ~50 minutes
Explore the labRecommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Cancer as a Neural Circuit Disease
Diffuse midline glioma: when development and cancer intersectRelate diffuse midline glioma to developmental cell states.
Supports: Glioma
Cancer as a Neural Circuit Disease
Neuronal activity feeds glioma growthInterpret activity-dependent growth and conditional NLGN3 dependence.
Supports: Glioma
Cancer as a Neural Circuit Disease
Cancer cells join neural circuitsSeparate functional synaptic evidence from cell identity.
Supports: Glioma
Nature · 2017
Venkatesh HS, Tam LT, Woo PJ, et al., Monje M
Why this matters: Tests NLGN3 dependency and shedding, with escape and model scope relevant.
DOI: 10.1038/nature24014