Research topic
Study of neural regulation of tumor growth and interactions among activity, glial development, and cancer.
Independent educational guide. Not affiliated with or endorsed by the universities, professors or laboratories described here. This collection reflects the material currently mapped on Socratic Learn.
Research at the intersection of neurodevelopment, glioma biology, neural activity, tumor microenvironment signaling, cancer neuroscience, and mechanism-guided therapies.
9 lessons · ~50 minutes
Explore the labRecommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Cancer as a Neural Circuit Disease
How do you study communication between neurons and cancer cells?Match experimental methods to structure, activity, and cell-state questions.
Supports: Cancer neuroscience
Cancer as a Neural Circuit Disease
Neuronal activity feeds glioma growthInterpret activity-dependent growth and conditional NLGN3 dependence.
Supports: Cancer neuroscience
Cancer as a Neural Circuit Disease
Cancer cells join neural circuitsSeparate functional synaptic evidence from cell identity.
Supports: Cancer neuroscience
Cancer as a Neural Circuit Disease
From cancer neuroscience to new therapiesDistinguish early GD2 CAR T activity from established clinical efficacy.
Supports: Cancer neuroscience
Cell · 2015
Venkatesh HS, Johung TB, Caretti V, et al., Monje M
Why this matters: Links controlled neuronal activity and secreted growth factors in mouse glioma models.
DOI: 10.1016/j.cell.2015.04.012
Cell · 2023
Winkler F, Venkatesh HS, Amit M, et al
Why this matters: Reviews diverse mechanisms and translational questions without flattening tumor contexts.
DOI: 10.1016/j.cell.2023.02.002