Research topic
Transient episodes of elevated beta activity whose duration may relate to impaired movement.
Independent educational guide. Not affiliated with or endorsed by the universities, professors or laboratories described here. This collection reflects the material currently mapped on Socratic Learn.
Human Motor Control and Neuromodulation Laboratory: linking quantitative movement measurements with implanted subthalamic local field potentials and neuromodulation to understand Parkinson’s disease and develop personalized adaptive therapies.
5 lessons · ~27 minutes
Explore the labRecommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Decoding and Restoring Movement in Parkinson’s Disease
Beta oscillations: a neural signature of impaired movementDistinguish beta power from threshold-defined burst duration.
Supports: Beta bursts
Brain 144(2):473–486 (online December 2020) · 2021
Kehnemouyi YM, Wilkins KB, Anidi CM, Anderson RW, Afzal MF, et al., Bronte-Stewart HM
Why this matters: Relates stimulation-associated changes in beta bursts to improved bradykinesia. The primer uses abstract-level evidence; an association does not establish a sole cause.
DOI: 10.1093/brain/awaa394
Brain Commun 7(4):fcaf266 · 2025
Wilkins KB, Petrucci MN, Lambert EF, Melbourne JA, Gala AS, Akella P, Parisi L, Cui C, Kehnemouyi YM, Hoffman SL, Aditham S, Diep C, Dorris HJ, Parker JE, Herron JA, Bronte-Stewart HM
Why this matters: Seven-participant investigational beta-burst-driven adaptive DBS study. Gait/freezing improved relative to stimulation OFF; group outcomes were comparable to continuous and random-adaptive stimulation, without universal superiority.
DOI: 10.1093/braincomms/fcaf266