Karl Deisseroth Lab
Karl DeisserothControlling, mapping and modeling neural circuits across cell types, space and behavior.
9 lessons · ~48 minutes
Explore the labResearch topic
Xenotransplantation
Interpreting human-organoid development and integration within a host model.
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Core background
Controlling, Mapping, and Modeling Neural Circuits
Xenocortication: building a developmental human-circuit modelExplain the experimental logic of the 2026 xenocortication study.
Supports: Xenotransplantation
Important papers
Nature 610:319–326 · 2022
Maturation and circuit integration of transplanted human cortical organoids
Revah O, Gore F, Kelley KW, et al., Deisseroth K, Pașca SP
Why this matters: Studies maturation and integration of human cortical organoids in a host model; collaborative work.
DOI: 10.1038/s41586-022-05277-w