Karl Deisseroth Lab
Karl DeisserothControlling, mapping and modeling neural circuits across cell types, space and behavior.
9 lessons · ~48 minutes
Explore the labResearch topic
Xenocortication
A collaborative developmental human-circuit model discussed in the existing primer.
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Recommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Core background
Controlling, Mapping, and Modeling Neural Circuits
Xenocortication: building a developmental human-circuit modelExplain the experimental logic of the 2026 xenocortication study.
Supports: Xenocortication
Controlling, Mapping, and Modeling Neural Circuits
What did xenocortication actually show?Identify which conclusions the xenocortication evidence supports.
Supports: Xenocortication
Important papers
Nature · 2026
Developmental xenocortication using human-derived organoids in mice
Kaganovsky K, Kelley KW, Gschwind T, Harary PM, et al., Deisseroth K, Pașca SP
Why this matters: A multi-group Stanford collaboration led by the Pașca lab, with Deisseroth among contributors; developmental models do not establish clinical efficacy.
DOI: 10.1038/s41586-026-11032-2