Research topic
Tabula Sapiens in biological measurement: Human cell atlases and reference transcriptomes, Tabula Sapiens and cross-tissue cellular diversity. Interpretation retains sampling, model, and validation limits.
Independent educational guide. Not affiliated with or endorsed by the universities, professors or laboratories described here. This collection reflects the material currently mapped on Socratic Learn.
Research develops biological measurement tools and applies them to single-cell genomics, genomic diagnostics, microbial ecology, and quantitative biological analysis. This independent primer distinguishes historical lab contributions, collaborative and consortium results, current research, and clinical screening from diagnosis.
6 lessons · ~29 minutes
Explore the labRecommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Measuring Life: From Single Cells to Liquid Biopsies
Building a map of the human body, one cell at a timeUse cell-atlas reference profiles while accounting for sampling and capture bias.
Supports: Tabula Sapiens
Science · 2022
The Tabula Sapiens Consortium (Jones RC, Karkanias J, Krasnow MA, Pisco AO, Quake SR, Salzman J, Yosef N, et al.)
Why this matters: CONSORTIUM PRIMARY RESULT: 483,152 cells from 24 tissues/organs, 475 annotated types and 15 donors. Sampling and dissociation limit coverage.
DOI: 10.1126/science.abl4896