Research topic
Immune repertoire sequencing in biological measurement: Immune repertoire sequencing and clonal dynamics. Interpretation retains sampling, model, and validation limits.
Independent educational guide. Not affiliated with or endorsed by the universities, professors or laboratories described here. This collection reflects the material currently mapped on Socratic Learn.
Research develops biological measurement tools and applies them to single-cell genomics, genomic diagnostics, microbial ecology, and quantitative biological analysis. This independent primer distinguishes historical lab contributions, collaborative and consortium results, current research, and clinical screening from diagnosis.
6 lessons · ~29 minutes
Explore the labRecommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Measuring Life: From Single Cells to Liquid Biopsies
From immune systems to microbiomes: what else can sequencing reveal?Interpret immune clone counts without inferring antigen or complete tissue coverage.
Supports: Immune repertoire sequencing
Sci Transl Med · 2013
Jiang N, He J, Weinstein JA, et al., Davis MM, Fisher DS, Quake SR
Why this matters: COLLABORATIVE PRIMARY RESULT: vaccination-associated antibody lineages; sequence expansion does not automatically reveal antigen specificity.
DOI: 10.1126/scitranslmed.3004794