Research topic
Single-molecule measurement in biological measurement: Single-molecule measurement and measurement-driven discovery. Interpretation retains sampling, model, and validation limits.
Independent educational guide. Not affiliated with or endorsed by the universities, professors or laboratories described here. This collection reflects the material currently mapped on Socratic Learn.
Research develops biological measurement tools and applies them to single-cell genomics, genomic diagnostics, microbial ecology, and quantitative biological analysis. This independent primer distinguishes historical lab contributions, collaborative and consortium results, current research, and clinical screening from diagnosis.
6 lessons · ~29 minutes
Explore the labRecommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Measuring Life: From Single Cells to Liquid Biopsies
Why better measurements change biologyExplain how microfluidic scale, isolation and valves change what can be measured.
Supports: Single-molecule measurement
PNAS · 2003
Braslavsky I, Hebert B, Kartalov E, Quake SR
Why this matters: HISTORICAL QUAKE-LAB PRIMARY RESULT: demonstrated sequence fingerprints up to five bases; not sole invention of all sequencing.
DOI: 10.1073/pnas.0230489100