Research topic
Microfluidics in biological measurement: Measurement technology, scale, and microfluidics. Interpretation retains sampling, model, and validation limits.
Independent educational guide. Not affiliated with or endorsed by the universities, professors or laboratories described here. This collection reflects the material currently mapped on Socratic Learn.
Research develops biological measurement tools and applies them to single-cell genomics, genomic diagnostics, microbial ecology, and quantitative biological analysis. This independent primer distinguishes historical lab contributions, collaborative and consortium results, current research, and clinical screening from diagnosis.
6 lessons · ~29 minutes
Explore the labRecommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Measuring Life: From Single Cells to Liquid Biopsies
Why better measurements change biologyExplain how microfluidic scale, isolation and valves change what can be measured.
Supports: Microfluidics
Science · 2000
Unger MA, Chou HP, Thorsen T, Scherer A, Quake SR
Why this matters: HISTORICAL QUAKE-LAB PRIMARY RESULT: multilayer valves and pumps enable parallel biological measurements.
DOI: 10.1126/science.288.5463.113
Science · 2002
Thorsen T, Maerkl SJ, Quake SR
Why this matters: HISTORICAL QUAKE-LAB PRIMARY RESULT: integrated chambers and valves automate many measurements.
DOI: 10.1126/science.1076996
Science · 2006
Ottesen EA, Hong JW, Quake SR, Leadbetter JR
Why this matters: COLLABORATIVE PRIMARY RESULT: Leadbetter-led multigene measurements of individual environmental bacteria.
DOI: 10.1126/science.1131370