Ngan F. Huang Lab
Ngan F. HuangCells, matrices and engineered environments for vascular and muscle regeneration.
6 lessons ยท ~46 minutes
Explore the labResearch topic
Mechanobiology
How cells sense and respond to forces and material mechanics.
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Core background
Cells, Matrices, and Regeneration
How can a material tell a cell what to do?At stress 100 Pa, strains 0.1 and 0.05 imply simple moduli 1,000 and 2,000 Pa.
Supports: Mechanobiology
Important papers
2022
Single-Cell Transcriptomic Census of Endothelial Changes Induced by Matrix Stiffness and the Association with Atherosclerosis
Zamani et al.
Why this matters: Examines stiffness-associated endothelial phenotypes; does not establish a universal mechanism.
DOI: 10.1002/adfm.202203069