Research topic
Single-cell genomics in biological measurement: Genome versus transcriptome and bulk versus single-cell measurement, Single-cell RNA sequencing, cell types, and cell states. Interpretation retains sampling, model, and validation limits.
Independent educational guide. Not affiliated with or endorsed by the universities, professors or laboratories described here. This collection reflects the material currently mapped on Socratic Learn.
Research develops biological measurement tools and applies them to single-cell genomics, genomic diagnostics, microbial ecology, and quantitative biological analysis. This independent primer distinguishes historical lab contributions, collaborative and consortium results, current research, and clinical screening from diagnosis.
6 lessons · ~29 minutes
Explore the labRecommended through the concepts linked to this topic. Each lesson belongs to an existing learning series.
Measuring Life: From Single Cells to Liquid Biopsies
Single-cell genomics: why one cell at a time mattersDistinguish genome, transcriptome and bulk versus single-cell information.
Supports: Single-cell genomics
PNAS · 2006
Warren L, Bryder D, Weissman IL, Quake SR
Why this matters: COLLABORATIVE PRIMARY RESULT: digital RT-PCR profiles individual hematopoietic progenitors.
DOI: 10.1073/pnas.0608512103